Lats2 Modulates Adipocyte Proliferation and Differentiation via Hippo Signaling
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چکیده
منابع مشابه
Lats2 Modulates Adipocyte Proliferation and Differentiation via Hippo Signaling
First identified in Drosophila and highly conserved in mammals, the Hippo pathway controls organ size. Lats2 is one of the core kinases of the Hippo pathway and plays major roles in cell proliferation by interacting with the downstream transcriptional cofactors YAP and TAZ. Although the function of the Hippo pathway and Lats2 is relatively well understood in several tissues and organs, less is ...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2013
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0072042